Translation initiation is the process of assembly of elongation-competent 80S ribosomes, in which the initiation codon is base-paired with the anticodon loop of initiator tRNA (Met-tRNAMeti) in the ribosomal P-site1.
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Eukaryotic translation initiation: Complex of small ribosomal subnit and initiator tRNA (bearing methionine) binds to 5' cap of mRNA. Complex scans from 5' to 3 ...
Translation initiation in eukaryotes is a highly regulated and complex stage of gene expression. It requires the action of at least 12 initiation factors ...
The structural and functional analysis of eukaryotic translation initiation factors reveals that they have most likely evolved to take advantage of the many RNA ...
The cap structure recruits the small ribosomal subunit (40S subunit) to the mRNA during translation initiation. It may also position the 40S subunits recruited ...